When Anya Corazon discovered a strange blue spider tattoo on her arm, she had no idea of what the arcane mark meant. Soon she discovered her strength and agility were boosted to near superhuman levels, and that she could cling to walls like a spider. Calling herself Arana (the Spanish word for 'Spider'), Anya took to the streets in a homemade costume comprised of a white-and-red spider t-shirt, black jeans, goggles, red fingerless gloves, and a backpack (to store her spider-shaped grapnel hooks and swing lines). Soon Arana discovered the true nature of the tattoo on her arm, when it formed a blue-and-red armor-like exoskeleton around her body. But when Arana's exoskeleton was ripped from her body by a villain called the Doomsday Man, she lost all her abilities. Anya soon tried to fight crime without powers in a sleek black-and-red spidery costume she was given by a former Spider-Woman, relying on her own gymnastic skills and her old spider-themed grapnel hooks to fight crime as Spider-Girl (a codename she only accepted as people always seemed to refer to her as Spider-Girl instead Arana). Her lack of powers placed her in harm's way on many of her adventures, but when a villain created a virus based on Spider-Man's DNA, Spider-Girl was infected and found herself once again imbued with spider-like abilities. Wearing a modified black-and-white version of her Spider-Girl costume, Anya used her new spider-strength, speed, agility, wall-crawling, and web-shooting powers as a truly super-powered Spider-Girl and a new member of the Avengers. Later Spider-Girl added a hooded cloak and a spider-symbol vest to her costume.